Shalabh Gupta, M.D.
Founder, Chief Executive Officer, President and Chairman of the Board of Directors
Shalabh Gupta, MD, founded Unicycive and has served as Chief Executive Officer, President, and director since August 2016. Previously, Dr. Gupta served in various other roles, including founder and Chief Executive Officer of Biocycive Inc.; a commercial strategist at Genentech, Inc.; equity researcher covering US pharmaceutical companies at UBS Investment Bank; and as an equity researcher covering biotechnology companies at Rodman & Renshaw (currently HC Wainwright). Dr. Gupta previously served as a medical advisor to Synageva BioPharma Corporation and as an advisor to New York University (NYU) Langone Medical Center’s Office of Technology Transfer. Dr. Gupta is also the founder and Chief Executive Officer of Globavir, a company with a diagnostic platform technology licensed from Stanford University, which partnered with Bio-Rad (NASDAQ: BIO) in 2016 and later with Cepheid (now part of Danaher Corporation, NYSE: DHR). Bio-Rad currently sells this technology as part of their RUO (Research Use Only) kits, and Danaher is advancing diagnostic technology through the regulatory approval process worldwide.
Dr. Gupta is an advisor to the UCSF Innovation Center, a role he has held since 2020. Since 2012, Dr. Gupta has also been an advisor to SPARK, Stanford University School of Medicine. Dr. Gupta previously served on the board of directors for the Beall Center for Innovation and Entrepreneurship at the University of California Irvine, Paul Merage School of Business.
Before his roles in business and finance, Dr. Gupta was an attending physician at New York University (“NYU”) Medical Center and a clinical faculty member at the NYU School of Medicine. Dr. Gupta was a board-certified physician currently licensed by the California State Medical Board.
Dr. Gupta completed his internship in Internal Medicine, medical residency in Physical Medicine and Rehabilitation, and research fellowship in Cardiopulmonary Rehabilitation at NYU School of Medicine. Dr. Gupta received his MPA in Health Care Finance and Management from NYU’s Robert F. Wagner Graduate School of Public Service and his MD from Jawaharlal Institute of Postgraduate Medical Education & Research, India.
Dr. Gupta has been in several leadership roles throughout his academic and professional career. He was elected president of the Resident Physicians Council during his residency training, representing approximately 1,500 resident physicians in physical medicine and rehabilitation across the US. He also also served on the Board of Directors at the Wagner Alumni Association.
Gaurav Aggarwal, M.D.
Gaurav Aggarwal, MD, brings decades of experience investing in private and public biopharmaceutical and medical device companies across the development spectrum. Most recently, he served as a Managing Director at Vivo Capital, a global healthcare investment firm. Previously, Dr. Aggarwal served as Managing Director with Investor Growth Capital, Partner with Panorama Capital, and Associate at JPMorgan Partners. He was an investor and previously served on the boards of Auspex Pharmaceuticals (acquired by Teva), Hyperion Therapeutics (acquired by Horizon), NextWave Pharmaceuticals (acquired by Pfizer), Piramed (acquired by Roche), and Flowcardia (acquired by CR Bard). Other successful investments include Amarin, ISTA Pharmaceuticals and Spinal Concepts. In addition to his role as an investor, Gaurav was the Chief Business Officer of Ocera Therapeutics, a publicly traded clinical stage company developing therapies for orphan liver conditions.
Dr. Aggarwal received his MD from Columbia University, College of Physicians & Surgeons, and his B.S. in Agricultural Economics from Cornell University.
Sara Kenkare-Mitra, PhD
Dr. Sara Kenkare-Mitra is a distinguished biotech/pharma drug developer and executive, currently serving as the President and Head of R&D at Alector for two years. With over 25 years of industry experience, she has dedicated her career to developing novel drugs and personalizing treatments. Her work spans the entire drug discovery and development spectrum, including the successful global filing and launch of multiple drugs during her 24-year tenure at Genentech/Roche. While she has a particular focus on Oncology, she has also worked in areas such as neurodegeneration, ophthalmology, and respiratory diseases.
Dr. Kenkare-Mitra's accomplishments are significant. She and her organizations have contributed to the filing of 11 BLA/NDA for novel drugs currently on the market, including Xolair, Tarceva, Avastin, Lucentis, Kadcyla, Venclexta, Vismodegib, Perjeta, Tecentriq, Ocrevus, and Polivy, as well as over 100 IND/CTA submissions for novel NMEs. She has also enabled the successful development and approval of more than 15 companion diagnostics and several novel diagnostic technologies at Genentech/Roche. She was instrumental in driving the early success of the antibody-drug conjugate platform at Genentech and was part of the team that led to the discovery of Kadcyla. Additionally, her team has been integral in driving collaborations and strategic partnerships, such as the one with Foundation Medicine.
Dr. Kenkare-Mitra's leadership and contributions to the field have earned her numerous accolades and memberships, including being elected a National Academy of Medicine (NAM) member and an AAAS fellow. She has also received awards for her leadership and influence from the San Francisco Business Times, Fierce Biotech, Endpoint News, AAPS, and has been celebrated as both a distinguished and Top 150 alumni at UCSF.
Beyond her industry work, Dr. Kenkare-Mitra is an Adjunct Full Professor at UCSF and Adjunct faculty at the University of Pacific. She has served on the board of several non-profit organizations, including AWIS and the Genentech Foundation, and co-founded two successful mentoring programs at Genentech. Her academic qualifications include a PhD in Pharmaceutical Chemistry from UCSF, a Fellowship in Clinical Pharmacology, and post-doctoral training at UCSF.
Sandeep “Steve” Laumas, M.D.
Steve Laumas has over two decades of experience in healthcare investments in both private and public companies and has served on the board of directors of publicly traded biotechnology companies, including BioXcel Therapeutics (Nasdaq: BTAI) and 9 Meters Biopharma (Nasdaq: NMTR).
Since 2014, Dr. Laumas has served on the board of directors of private and publicly traded biotechnology companies. In 2008, Dr. Laumas founded Bearing Circle Capital, an investment vehicle, and has served as its Managing Director since such time. Dr. Laumas began his career at Goldman Sachs & Co. in 1996 as an equity analyst in the healthcare investment banking division, working on mergers & acquisitions and corporate finance transactions before transitioning to the healthcare equity research division. After leaving Goldman Sachs in 2000, Dr. Laumas moved to the buy side as an analyst at Balyasny Asset Management from 2001 to 2003. Dr. Laumas was a Managing Director of North Sound Capital from 2003 to 2007 and was responsible for the global healthcare investment portfolio. Dr. Laumas has served as a member of the board of directors of private and public healthcare companies, including Parkway Holdings Ltd. (2010), SRL Ltd. (2011-2012), 9 Meters Biopharma, Inc. (Nasdaq: NMTR) (2018-present) and BioXcel Therapeutics, Inc. (Nasdaq: BTAI) (2017-present). Dr. Laumas received his A.B. in Chemistry from Cornell University in 1990, his MD from Albany Medical College in 1995 with a research year at the Dana-Farber Cancer Institute, and he completed his medical internship in 1996 from the Yale University School of Medicine.
John Ryan, M.D., Ph.D.
John Ryan is Executive Vice President, Chief Medical Officer at Kadmon. Dr. Ryan has more than 20 years of experience in drug discovery and development, including expertise in translational medicine and cancer biology. Before joining Kadmon, he was Chief Medical Officer and Senior Vice President of Cerulean Pharma, Inc. from March 2010 and Acting Chief Medical Officer of Cerulean from July 2009 to March 2010. Dr. Ryan held the role of Chief Medical Officer at Aveo Pharmaceuticals, Inc. beginning in April 2006. Prior to Aveo, he served as Senior Vice President of Translational Research at Wyeth (formerly Genetics Institute). At Wyeth, he served as head of the new Department of Experimental Medicine, which was created to explore new technologies, such as pharmacogenomics, in exploratory clinical trials, to work closely with the FDA on clinical pharmacogenomics, and to bridge discovery and development with the creation of new biomarkers. Dr. Ryan served as an Executive Director of Clinical Research at Merck Research Laboratories. He served as Member of the Scientific Advisory Board of Arqule, Inc. and as Member of the Scientific Advisory Board of Expression Analysis, Inc. He was a Professor in the Department of Internal Medicine at Pennsylvania School of Medicine and Yale University School of Medicine from 1977 to 1989. Dr. Ryan received his bachelor’s degree from Yale University. He holds a Ph.D. in Molecular Biophysics from Yale University and an MD from the University of California.